You did not say how big your second drive is but the first thing I would be doing is downloading and running a virus detector and running it on your secon drive. Do this by Going to AVG free ( http://free.avg.com/ ) and clicking on the download button, after several windows open and you continue to sellect download, you will be asked do you want to install it on "C" sellect your other drive and download it there. This way only a few kbs will be placed on "C" If you have the original CDs for your other programs like Office, you can load them to the other drive as well and then delete them from